http://www.theonlinevet.com
There is a commonly prescribed veterinary drug, Tramadol, which may not be effective. A new study published in JAVMA, concluded: ‘Lack of effectiveness of tramadol hydrochloride for the treatment of pain and joint dysfunction in dogs with chronic osteoarthritis’

Study is here: https://avmajournals.avma.org/doi/abs/10.2460/javma.252.4.427

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